With the ability to detect over 70 types of cancer via the presence of Circulating Tumour Cells (CTCs), TruCheck is revolutionising the field of early cancer detection.
The TruCheck test does not detect all cancer types and not all cancer types can be detected in the blood. False negative and false positive results do occur.
A ‘Negative for Malignancy’ outcome from the TruCheck test implies that, within the test’s defined accuracy bounds, no Circulating Tumor Cells (CTCs) were discerned in the patient’s blood sample. This likely points to the absence of an active cancer that the test can identify at the time of testing. However, it’s crucial to bear in mind that TruCheck may not detect certain cancers. As such, a ‘negative’ result does not entirely eliminate the possibility of those specific cancers. Therefore, regular health evaluations and any cancer screenings advised by you as their healthcare provider continue to be of utmost importance.
A ‘Positive for Malignancy’ outcome from the TruCheck test indicates the detection of Circulating Tumor Cells (CTCs) in the patient’s blood sample, signifying the presence of cancer. Alongside this finding, the test provides an analytical assessment suggesting the probable organ of origin and the type of malignancy, aiming to accurately predict the organ potentially affected by the cancer. However, this is a screening test, not a definitive diagnostic tool. In the event of a ‘positive’ result, you should review the TruCheck report for your patient and advise on further steps, which may involve additional diagnostic tests. Only a healthcare professional can confirm a cancer diagnosis.
The TruCheck test is advised for application in adults with an increased risk of cancer. It’s meant to complement, not replace, standard cancer screenings. TruCheck is not suggested for individuals who are below the age of 40, have cancer currently or have had treatment for any type of cancer previously.
TruCheck test results will be dispatched to the healthcare provider who placed the order, approximately two weeks post the receipt of the patient’s sample at the laboratory. Healthcare providers can access these results through the Provider Portal. Users of the Provider Portal have the option to establish email notifications for alerting when new results are available.
The false positive rate is the percentage of individuals without cancer who get a “Cancer Detected” result.
The TruCheck test has a <1% false positive rate, implying that 1 out of 100 people who do not have cancer will receive a “Cancer Detected” result. This low false positive rate helps limit the possibility of a cancer-free individual receiving a “Cancer Detected” result, thereby minimising unnecessary follow-up diagnostic procedures to confirm the presence of cancer.
The predicted Cancer Signal Source (CSS) assists in determining the next steps for cancer confirmation. With a Cancer Signal Detected result, TruCheck predicts the Cancer Signal Source. This prediction provides insights about the tissue type or organ related to the cancer signal. In patients with a confirmed cancer diagnosis following a TruCheck Cancer Signal Detected result, the test was accurate 88% of the time in predicting the Cancer Signal Source. If the predicted Cancer Signal Source does not result in a cancer diagnosis, it could mean that the cancer could not be detected or is located elsewhere.
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The TruCheck test is suggested for use in adults with a higher risk of cancer, typically those aged 50 or above. TruCheck does not detect all types of cancers and should be considered a supplemental tool alongside routine cancer screening tests advised by your healthcare provider. The primary goal of TruCheck is to identify cancer signals and predict their origin within the body. It is not recommended for use in individuals who are pregnant, under the age of 40, or currently undergoing active cancer treatment.
Results must be analysed by a healthcare professional, taking into account the patient’s medical history, clinical signs, and symptoms. A result of “No Cancer Signal Detected” does not definitively exclude the presence of cancer. Likewise, a “Cancer Signal Detected” result necessitates further diagnostic evaluation through established medical procedures (such as imaging) to confirm the presence of cancer.
In cases where further testing does not confirm cancer, this could indicate either the absence of cancer or that the test was unable to detect it, including situations where the cancer is located in a different part of the body. Be aware that false-positive (a cancer signal detected when cancer is not present) and false-negative (a cancer signal not detected when cancer is present) results can occur.
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